Stelera (ustekinumab) is an innovative biologic therapy used to treat several chronic autoimmune diseases. If you or a loved one has been diagnosed with an autoimmune condition, you may be considering Stelera as a treatment option. This blog post will dive into what Stelera is, how it works, and the four key conditions it helps manage. Additionally, we’ll discuss how our specialty infusion pharmacy can support you throughout your treatment journey.
What is Stelera?
Stelera is a biologic medication, meaning it is created from living cells and specifically targets immune system proteins that cause inflammation. It works by inhibiting interleukin-12 (IL-12) and interleukin-23 (IL-23), two cytokines involved in the immune response. These cytokines are responsible for driving inflammation in certain autoimmune diseases, and by blocking them, Stelera helps control the immune system and reduce disease activity.
Stelera is typically administered via infusion or injection, offering a targeted approach to managing chronic autoimmune diseases.
How Does it Work?
Stelera works by modulating the immune system’s response, preventing the overproduction of pro-inflammatory cytokines like IL-12 and IL-23. This helps reduce inflammation and the associated symptoms in the skin, joints, and digestive tract. By specifically targeting these immune pathways, Stelera provides more effective and targeted treatment with fewer side effects compared to other treatment options.
Conditions Treated
Stelera has been approved for the treatment of four primary autoimmune conditions, each affecting different areas of the body. Let’s take a closer look at how Stelera helps manage these conditions:
1. Psoriasis: Managing Skin Flare-Ups
Psoriasis is a chronic autoimmune condition that causes the skin cells to multiply too quickly, leading to thick, scaly patches of skin. Stelera targets the immune system’s overactivity, reducing the inflammation that causes these skin cells to grow rapidly. By inhibiting IL-12 and IL-23, Stelera helps control flare-ups and promotes smoother, clearer skin.
2. Psoriatic Arthritis: Easing Joint Pain and Inflammation
Psoriatic arthritis (PsA) is a form of arthritis that often occurs in people with psoriasis. It causes inflammation in the joints, leading to pain, stiffness, and reduced mobility. Stelera helps manage PsA by targeting the same immune response that triggers both skin and joint inflammation. This treatment can reduce joint pain, improve function, and prevent further damage to the joints.
3. Crohn’s Disease: Reducing Inflammation in the Digestive Tract
Crohn’s disease is a type of inflammatory bowel disease (IBD) that causes chronic inflammation in the gastrointestinal (GI) tract. This can lead to symptoms like abdominal pain, diarrhea, and weight loss. Stelera targets the inflammatory cytokines in the GI tract, helping to reduce swelling and discomfort while allowing the tissue to heal. This can lead to fewer flare-ups and an improved quality of life for those with Crohn’s disease.
4. Ulcerative Colitis: Managing Chronic Bowel Inflammation
Similar to Crohn’s disease, ulcerative colitis is an inflammatory bowel disease, but it specifically affects the colon and rectum. Stelera works in the same way for ulcerative colitis, reducing inflammation in the colon to prevent symptoms like painful cramping, bleeding, and diarrhea. By addressing the root cause of the inflammation, Stelera helps provide relief and control over the disease.
Benefits of Stelera Treatment
Stelera offers numerous benefits for patients living with autoimmune conditions, including:
- Targeted Immune Modulation: By specifically targeting IL-12 and IL-23, Stelera offers a more precise and effective treatment option than traditional therapies.
- Reduced Inflammation: Stelera helps reduce inflammation in the skin, joints, and digestive system, leading to symptom relief and fewer flare-ups.
- Improved Quality of Life: With reduced symptoms and disease activity, many patients find they experience better overall health and well-being.
- Long-Term Management: Stelera can help maintain disease control over time, minimizing the need for frequent flare-up treatments or emergency interventions.
What to Expect During Your Infusion Treatment
For patients receiving Stelera through infusion therapy, the process is straightforward and carefully monitored. Here’s what you can expect:
- The Infusion Process: Stelera infusions are typically administered in a healthcare setting, like a specialty infusion pharmacy. An intravenous (IV) line will be inserted, and the medication will be infused slowly over several hours. The first infusion may take longer, while subsequent treatments may take less time.
- Pre-Treatment Preparations: Before receiving an infusion, your healthcare provider will review your medical history and any current medications. It’s important to inform your doctor about any allergies or previous reactions to biologics.
- Monitoring During the Infusion: During the infusion, healthcare providers will monitor your vital signs, including blood pressure, heart rate, and temperature. They will also keep an eye on you for any signs of side effects, such as fever, chills, or nausea.
- Post-Treatment Care: After the infusion, you may experience mild side effects, such as fatigue or headaches, but these typically resolve within a few days. Your healthcare provider will provide guidance on managing any post-treatment symptoms.
Potential Side Effects
Stelera is generally well-tolerated, but like any medication, it can cause side effects. Common side effects may include:
- Headache
- Fatigue
- Nausea
- Upper respiratory infections (e.g., cold or sore throat)
In rare cases, Stelera can cause more serious side effects, such as allergic reactions or an increased risk of infections. It’s important to communicate with your healthcare provider if you experience any unusual symptoms.
How Often Do You Need Infusions?
The frequency of Stelera infusions depends on your specific condition and treatment plan. For many patients, infusions are given every 8 to 12 weeks after the initial loading doses. Your healthcare provider will determine the best schedule for your treatment.
Cost and Insurance Coverage for Stelera Treatment
The cost of Stelera treatment can vary depending on several factors, including your dosage and the frequency of infusions. Many insurance plans do cover biologic treatments like Stelera, but it’s important to confirm your insurance coverage before beginning treatment. Our specialty infusion pharmacy team is here to help guide you through the process and assist with insurance verification.
Final Thoughts
Stelera is an effective treatment option for managing autoimmune diseases like psoriasis, psoriatic arthritis, Crohn’s disease, and ulcerative colitis. By targeting the underlying immune response that causes inflammation, Stelera provides relief from symptoms and helps prevent long-term damage. If you’re considering Stelera for your treatment plan, consult with your healthcare provider to determine if it’s the right choice for you.
At Vital Care of Roanoke, we provide the personalized care and support you need throughout your Stelera treatment journey. Contact us today to learn more about Stelera and how we can help you manage your autoimmune disease with compassion and convenience.
Key Takeaways:
- Stelera is a biologic therapy used to treat psoriasis, psoriatic arthritis, Crohn’s disease, and ulcerative colitis.
- It works by blocking the inflammatory cytokines IL-12 and IL-23.
- Stelera is typically administered through an infusion and is carefully monitored for safety.
- The frequency of Stelera infusions depends on your condition and treatment plan.
- Stelera is covered by most insurance plans, but it’s important to verify coverage.
